Effects of a Primary Care Antimicrobial Stewardship Program on Meticillin-Resistant Staphylococcus aureus Strains across a Region of Catalunya (Spain) over 5 Years.
Alfredo Jover-SáenzMaría Ramírez-HidalgoAlba Bellés BellésEsther Ribes MurilloMeritxell Batlle BoschAnna Ribé MiróAlba Mari LópezJosé Cayado CabanillasNeus Piqué PalacínSònia Garrido-CalvoMireia Ortiz VallsMaría Isabel Gracia VilasLaura Gros NavésMaría Jesús Javierre CaudevillaLidia Montull NavarroCecilia Bañeres ArgilesPilar Vaqué CastillaJosé Javier Ichart TomásMireia Saura CodinaEster Andreu MayorRoser Martorell SoléAna Vena MartínezJosé Manuel Albalad SamperSusana Cano MarrónCristina Soler ElcachoAndrés Rodríguez GarrochoGemma Terrer ManriqueAntoni Solé CurcóDavid de la Rica EscuinMaría José Estadella ServallsAna M Figueres FarrenyLuís Miguel Montaña EstebanLidia Sanz BorrellArancha Morales ValleMercè Pallerola PlanesAly HamadiFrancesc Pujol AymerichFrancisca Toribio RedondoMaría Cruz Urgelés CastillónJuan Valgañon PalaciosMarc Olivart ParejoJoan Torres-Puig-Grosnull The P-Ilehrda Groupnull On Behalf Of Clinical Microbiology And Antibiotic Resistance Group-IRBLleida-Published in: Antibiotics (Basel, Switzerland) (2024)
Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant Staphylococcus aureus (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact.
Keyphrases
- staphylococcus aureus
- methicillin resistant staphylococcus aureus
- primary care
- randomized controlled trial
- escherichia coli
- biofilm formation
- healthcare
- quality improvement
- systematic review
- physical activity
- climate change
- risk assessment
- machine learning
- electronic health record
- pseudomonas aeruginosa
- hiv testing