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A catastrophic seronegative anti-phospholipid syndrome: case and literature review.

Vanda PintoAugusto MinistroNuno Reis CarreiraAna CardosoCatarina Sousa GonçalvesMickael HenriquesJoão RatoEmanuel SilvaLuís Mendes Pedro
Published in: Thrombosis journal (2021)
Catastrophic APS develops quickly, with multiorgan involvement and high mortality rate. The presented case poses a multidisciplinary challenge, with the surgical approach of extra-anatomical revascularization being less invasive and guaranteeing immediate perfusion of the lower limbs. Although the serological tests were negative for anti-phospholipid antibodies, this case hardly fits into another diagnosis. Therefore, it was treated as a catastrophic APS, having shown a favorable evolution.
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