A catastrophic seronegative anti-phospholipid syndrome: case and literature review.
Vanda PintoAugusto MinistroNuno Reis CarreiraAna CardosoCatarina Sousa GonçalvesMickael HenriquesJoão RatoEmanuel SilvaLuís Mendes PedroPublished in: Thrombosis journal (2021)
Catastrophic APS develops quickly, with multiorgan involvement and high mortality rate. The presented case poses a multidisciplinary challenge, with the surgical approach of extra-anatomical revascularization being less invasive and guaranteeing immediate perfusion of the lower limbs. Although the serological tests were negative for anti-phospholipid antibodies, this case hardly fits into another diagnosis. Therefore, it was treated as a catastrophic APS, having shown a favorable evolution.