Tissue-engineered and autologous pericardium in congenital heart surgery: comparative histopathological study of human vascular explants.
Katja EildermannMaksim DurashovKira KuschnerusAndrea PoppeViktoria WeixlerJoachim PhotiadisMatthias SiglerPeter MurinPublished in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2024)
Our results confirm the superior biocompatibility of human autologous patches and highlight discernible variations in the changes of patch material and the cellular response to patch material between bovine and equine patches. Our approach implements the semi-quantitative scoring of various aspects of biocompatibility, facilitating a comparative quantitative analysis across all types of patches, despite their inherent differences.