AQP9 suppresses hepatocellular carcinoma cell invasion through inhibition of hypoxia-inducible factor 1α expression under hypoxia.

Yanzhi QianFengchao LiuWenguang ZhangXi ZhengShengtao LiaoLin LvZhechuan Mei

Published in: Journal of gastroenterology and hepatology (2020)

These data suggest that AQP9 acts as a tumor suppressor in HCC invasion via the regulation of HIF-1α expression in the tumor hypoxic microenvironment.

Keyphrases

poor prognosis
endothelial cells
stem cells
binding protein
signaling pathway
electronic health record
big data
machine learning