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Genes uniquely expressed in human growth plate chondrocytes uncover a distinct regulatory network.

Bing LiKarthika BalasubramanianDeborah KrakowDaniel H Cohn
Published in: BMC genomics (2017)
Our findings revealed a complex gene regulatory network controlling skeletal development whereby transcription factors, enhancers and lncRNAs participate in chondrogenesis by transcriptional regulation of key genes. Additionally, the cartilage-selective genes represent candidate genes for unsolved human skeletal disorders.
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