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Listen to your gut: Antibodies against gut commensals predict type 1 diabetes onset and therapeutic responses to T cell modulation.

Rachael A Clark
Published in: Science immunology (2023)
Immune responses to gut bacteria are associated with development of type 1 diabetes and predict the effectiveness of teplizumab, an anti-CD3 antibody, in delaying diabetes onset.
Keyphrases
  • type diabetes
  • immune response
  • glycemic control
  • cardiovascular disease
  • randomized controlled trial
  • systematic review
  • insulin resistance
  • toll like receptor
  • inflammatory response
  • metabolic syndrome