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Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans.

Christal N DavisZeal JinwalaAlexander S HatoumSylvanus ToikumoArpana AgrawalChristopher T RentschHoward J EdenbergJames W BaurleyEmily E HartwellRichard C CristJoshua C GrayAmy C JusticeJoshua C GrayRachel L KemberHenry R Kranzler
Published in: medRxiv : the preprint server for health sciences (2024)
Candidate genes from the approved genetic risk algorithm do not meet standards of reasonable clinical efficacy in assessing risk of opioid use disorder.
Keyphrases
  • machine learning
  • deep learning
  • drug administration
  • neural network
  • copy number