Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans.
Christal N DavisZeal JinwalaAlexander S HatoumSylvanus ToikumoArpana AgrawalChristopher T RentschHoward J EdenbergJames W BaurleyEmily E HartwellRichard C CristJoshua C GrayAmy C JusticeJoshua C GrayRachel L KemberHenry R KranzlerPublished in: medRxiv : the preprint server for health sciences (2024)
Candidate genes from the approved genetic risk algorithm do not meet standards of reasonable clinical efficacy in assessing risk of opioid use disorder.