Rachel L Kember (Rachel Kember)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 98

Top Venues

medRxiv : the preprint server for health sciences

Nature human behaviour

Nature medicine

Journal of the American Heart Association

University of Pennsylvania

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania Mar 01 2017

United States

Research Associate :: Department of Genetics

University of Pennsylvania Jan 25 2012 - Feb 28 2017

United States

Postdoctoral Fellow :: Department of Genetics

Publications

Christal N Davis, Zeal Jinwala, Alexander S Hatoum, Sylvanus Toikumo, Arpana Agrawal, Christopher T Rentsch, Howard J Edenberg, James W Baurley, Emily E Hartwell, Richard C Crist, Joshua C Gray, Amy C Justice, Rachel L Kember, Henry R Kranzler
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans. medRxiv : the preprint server for health sciences (2024)
Christal N Davis, Sylvanus Toikumo, Alexander S Hatoum, Yousef Khan, Benjamin K Pham, Shreya R Pakala, Kyra L Feuer, Joshua C Gray, Sandra Sanchez-Roige, Rachel L Kember, Henry R Kranzler
Multivariate, Multi-omic Analysis in 799,429 Individuals Identifies 134 Loci Associated with Somatoform Traits. medRxiv : the preprint server for health sciences (2024)
Christal N Davis, Yousef Khan, Sylvanus Toikumo, Zeal Jinwala, Dorret I Boomsma, Daniel F Levey, Joshua C Gray, Rachel L Kember, Henry R Kranzler
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra. medRxiv : the preprint server for health sciences (2024)
Benjamin C Reiner, Samar N Chehimi, Riley Merkel, Sylvanus Toikumo, Wade H Berrettini, Henry R Kranzler, Sandra Sanchez-Roige, Rachel L Kember, Heath D Schmidt, Richard C Crist
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens. bioRxiv : the preprint server for biology (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association 13 (4) (2024)
Anurag Verma, Jennifer E Huffman, Alex Rodriguez, Mitchell Conery, Molei Liu, Yuk-Lam Anne Ho, Youngdae Kim, David A Heise, Lindsay A Guare, Vidul Ayakulangara Panickan, Helene Garcon, Franciel Linares, Lauren Costa, Ian Goethert, Ryan Tipton, Jacqueline P Honerlaw, Laura Davies, Stacey B Whitbourne, Jeremy Cohen, Daniel C Posner, Rahul Sangar, Michael Murray, Xuan Wang, Daniel R Dochtermann, Poornima Devineni, Yunling Shi, Tarak Nath Nandi, Themistocles L Assimes, Charles A Brunette, Robert J Carrol, Royce E Clifford, Scott L Duvall, Joshua C Gray, Adriana M Hung, Sudha K Iyengar, Jacob Joseph, Rachel L Kember, Henry R Kranzler, Colleen M Kripke, Daniel F Levey, Shiuh-Wen Luoh, Victoria C Merritt, Cassie Overstreet, Joseph D Deak, Struan F A Grant, Renato Polimanti, Panagiotis Roussos, Gabrielle Shakt, Yan V Sun, Noah L Tsao, Sanan Venkatesh, Georgios Voloudakis, Amy Justice, Edmon Begoli, Rachel B Ramoni, Georgia Tourassi, Saiju Pyarajan, Philip S Tsao, Christopher J O'Donnell, Sumitra Muralidhar, Jennifer Moser, Juan P Casas, Alexander G Bick, Wei Zhou, Tianxi Cai, Benjamin F Voight, Kelly Cho, John Michael Gaziano, Ravi K Madduri, Scott M Damrauer, Katherine P Liao
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (New York, N.Y.) 385 (6706) (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association 13 (4) (2024)
Anurag Verma, Jennifer E Huffman, Alex Rodriguez, Mitchell Conery, Molei Liu, Yuk-Lam Anne Ho, Youngdae Kim, David A Heise, Lindsay A Guare, Vidul Ayakulangara Panickan, Helene Garcon, Franciel Linares, Lauren Costa, Ian Goethert, Ryan Tipton, Jacqueline P Honerlaw, Laura Davies, Stacey B Whitbourne, Jeremy Cohen, Daniel C Posner, Rahul Sangar, Michael Murray, Xuan Wang, Daniel R Dochtermann, Poornima Devineni, Yunling Shi, Tarak Nath Nandi, Themistocles L Assimes, Charles A Brunette, Robert J Carrol, Royce E Clifford, Scott L Duvall, Joshua C Gray, Adriana M Hung, Sudha K Iyengar, Jacob Joseph, Rachel L Kember, Henry R Kranzler, Colleen M Kripke, Daniel F Levey, Shiuh-Wen Luoh, Victoria C Merritt, Cassie Overstreet, Joseph D Deak, Struan F A Grant, Renato Polimanti, Panagiotis Roussos, Gabrielle Shakt, Yan V Sun, Noah L Tsao, Sanan Venkatesh, Georgios Voloudakis, Amy Justice, Edmon Begoli, Rachel B Ramoni, Georgia Tourassi, Saiju Pyarajan, Philip S Tsao, Christopher J O'Donnell, Sumitra Muralidhar, Jennifer Moser, Juan P Casas, Alexander G Bick, Wei Zhou, Tianxi Cai, Benjamin F Voight, Kelly Cho, John Michael Gaziano, Ravi K Madduri, Scott M Damrauer, Katherine P Liao
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (New York, N.Y.) 385 (6706) (2024)
Dora Koller, Eleni Friligkou, Brendan Stiltner, Gita A Pathak, Solveig Løkhammer, Daniel F Levey, Hang Zhou, Alexander S Hatoum, Joseph D Deak, Rachel L Kember, Jorien L Treur, Henry R Kranzler, Emma C Johnson, Murray B Stein, Joshua C Gray, Renato Polimanti
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders. Molecular psychiatry (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine 30 (4) (2024)
Dora Koller, Eleni Friligkou, Brendan Stiltner, Gita A Pathak, Solveig Løkhammer, Daniel F Levey, Hang Zhou, Alexander S Hatoum, Joseph D Deak, Rachel L Kember, Jorien L Treur, Henry R Kranzler, Emma C Johnson, Murray B Stein, Joshua C Gray, Renato Polimanti
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders. Molecular psychiatry (2024)
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joshua C Gray, Henry R Kranzler, Rachel L Kember
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sarah Ramirez, Naomi Shifman, Daniel F Levey, Joshua C Gray, Emily E Hartwell, Rachel L Kember
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence. Nature human behaviour 8 (8) (2024)
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joshua C Gray, Henry R Kranzler, Rachel L Kember
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits. medRxiv : the preprint server for health sciences (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour 8 (6) (2024)
Yousef Khan, Christal N Davis, Zeal Jinwala, Kyra L Feuer, Sylvanus Toikumo, Emily E Hartwell, Sandra Sanchez-Roige, Roseann E Peterson, Alexander S Hatoum, Henry R Kranzler, Rachel L Kember
Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample. medRxiv : the preprint server for health sciences (2024)
Dora Koller, Eleni Friligkou, Brendan Stiltner, Gita A Pathak, Solveig Løkhammer, Daniel F Levey, Hang Zhou, Alexander S Hatoum, Joseph D Deak, Rachel L Kember, Jorien L Treur, Henry R Kranzler, Emma C Johnson, Murray B Stein, Joshua C Gray, Renato Polimanti
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders. Molecular psychiatry (2024)
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sarah Ramirez, Naomi Shifman, Daniel F Levey, Joshua C Gray, Emily E Hartwell, Rachel L Kember
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence. Nature human behaviour (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association 13 (4) (2024)
Christal N Davis, Yousef Khan, Sylvanus Toikumo, Zeal Jinwala, Dorret I Boomsma, Daniel F Levey, Joshua C Gray, Rachel L Kember, Henry R Kranzler
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra. Research square (2024)
Yousef Khan, Christal N Davis, Zeal Jinwala, Kyra L Feuer, Sylvanus Toikumo, Emily E Hartwell, Sandra Sanchez-Roige, Roseann E Peterson, Alexander S Hatoum, Henry R Kranzler, Rachel L Kember
Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample. medRxiv : the preprint server for health sciences (2024)
Christal N Davis, Sylvanus Toikumo, Alexander S Hatoum, Yousef Khan, Benjamin K Pham, Shreya R Pakala, Kyra L Feuer, Joshua C Gray, Sandra Sanchez-Roige, Rachel L Kember, Henry R Kranzler
Multivariate, Multi-omic Analysis in 799,429 Individuals Identifies 134 Loci Associated with Somatoform Traits. medRxiv : the preprint server for health sciences (2024)
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sarah Ramirez, Naomi Shifman, Daniel F Levey, Joshua C Gray, Emily E Hartwell, Rachel L Kember
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence. Nature human behaviour (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine 30 (4) (2024)
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joshua C Gray, Henry R Kranzler, Rachel L Kember
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits. medRxiv : the preprint server for health sciences (2024)
Christal N Davis, Yousef Khan, Sylvanus Toikumo, Zeal Jinwala, Dorret I Boomsma, Daniel F Levey, Joshua C Gray, Rachel L Kember, Henry R Kranzler
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra. Research square (2024)
Christal N Davis, Yousef Khan, Sylvanus Toikumo, Zeal Jinwala, Dorret I Boomsma, Daniel F Levey, Joshua C Gray, Rachel L Kember, Henry R Kranzler
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra. medRxiv : the preprint server for health sciences (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine 30 (4) (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour 8 (6) (2024)
Bao Khanh Trang, Alessandra Chesi, Sylvanus Toikumo, James A Pippin, Matthew C Pahl, Joan M O'Brien, Laufey T Amundadottir, Kevin K Brown, Wenli Yang, Jaclyn E Welles, Dominic Santoleri, Paul M Titchenell, Patrick Seale, Babette S Zemel, Yadav Wagley, Kurt D Hankenson, Klaus H Kaestner, Stewart A Anderson, Matthew S Kayser, Andrew D Wells, Henry R Kranzler, Rachel L Kember, Struan F A Grant
Shared and unique 3D genomic features of substance use disorders across multiple cell types. medRxiv : the preprint server for health sciences (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine 30 (4) (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour 8 (6) (2024)
Henry R Kranzler, Christal N Davis, Richard Feinn, Zeal Jinwala, Yousef Khan, Ariadni Oikonomou, Damaris Silva-Lopez, Isabel Burton, Morgan Dixon, Jackson Milone, Sarah Ramirez, Naomi Shifman, Daniel F Levey, Joshua C Gray, Emily E Hartwell, Rachel L Kember
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence. Nature human behaviour 8 (8) (2024)
Dora Koller, Eleni Friligkou, Brendan Stiltner, Gita A Pathak, Solveig Løkhammer, Daniel F Levey, Hang Zhou, Alexander S Hatoum, Joseph D Deak, Rachel L Kember, Jorien L Treur, Henry R Kranzler, Emma C Johnson, Murray B Stein, Joshua C Gray, Renato Polimanti
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders. Molecular psychiatry (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association 13 (4) (2024)
Emily E Hartwell, Zeal Jinwala, Jackson Milone, Sarah Ramirez, Joshua C Gray, Henry R Kranzler, Rachel L Kember
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Christal N Davis, Zeal Jinwala, Alexander S Hatoum, Sylvanus Toikumo, Arpana Agrawal, Christopher T Rentsch, Howard J Edenberg, James W Baurley, Emily E Hartwell, Richard C Crist, Joshua C Gray, Amy C Justice, Rachel L Kember, Henry R Kranzler
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans. medRxiv : the preprint server for health sciences (2024)
Sylvanus Toikumo, Mariela V Jennings, Benjamin K Pham, Hyunjoon Lee, Travis T Mallard, Sevim B Bianchi, John J Meredith, Laura Vilar-Ribó, Heng Xu, Alexander S Hatoum, Emma C Johnson, Vanessa M Pazdernik, Zeal Jinwala, Shreya R Pakala, Brittany S Leger, Maria Niarchou, Michael Ehinmowo, null null, Greg D Jenkins, Anthony Batzler, Richard Pendegraft, Abraham A Palmer, Hang Zhou, Joanna M Biernacka, Brandon J Coombes, Joshua C Gray, Ke Xu, Dana B Hancock, Nancy J Cox, Jordan W Smoller, Lea K Davis, Amy C Justice, Henry R Kranzler, Rachel L Kember, Sandra Sanchez-Roige
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes. Nature human behaviour (2024)
Gabrielle Shakt, Noah L Tsao, Michael G Levin, Venexia M Walker, Rachel L Kember, Derek M Klarin, Philip S Tsao, Benjamin F Voight, Salvatore T Scali, Scott M Damrauer
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors. Journal of the American Heart Association 13 (4) (2024)
Bao Khanh Trang, Alessandra Chesi, Sylvanus Toikumo, James A Pippin, Matthew C Pahl, Joan M O'Brien, Laufey T Amundadottir, Kevin K Brown, Wenli Yang, Jaclyn E Welles, Dominic Santoleri, Paul M Titchenell, Patrick Seale, Babette S Zemel, Yadav Wagley, Kurt D Hankenson, Klaus H Kaestner, Stewart A Anderson, Matthew S Kayser, Andrew D Wells, Henry R Kranzler, Rachel L Kember, Struan F A Grant
Shared and unique 3D genomic features of substance use disorders across multiple cell types. medRxiv : the preprint server for health sciences (2024)
Sylvanus Toikumo, Rachel Vickers-Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E Hartwell, Mirko Pavicic Venegas, Kyle A Sullivan, Ke Xu, Daniel A Jacobson, Joshua C Gray, Christopher T Rentsch, null null, Eli Stahl, Martin Cheatle, Hang Zhou, Stephen G Waxman, Amy C Justice, Rachel L Kember, Henry R Kranzler
A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature medicine 30 (4) (2024)
Christal N Davis, Zeal Jinwala, Alexander S Hatoum, Sylvanus Toikumo, Arpana Agrawal, Christopher T Rentsch, Howard J Edenberg, James W Baurley, Emily E Hartwell, Richard C Crist, Joshua C Gray, Amy C Justice, Joshua C Gray, Rachel L Kember, Henry R Kranzler
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans. medRxiv : the preprint server for health sciences (2024)
Benjamin C Reiner, Samar N Chehimi, Riley Merkel, Sylvanus Toikumo, Wade H Berrettini, Henry R Kranzler, Sandra Sanchez-Roige, Rachel L Kember, Heath D Schmidt, Richard C Crist
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens. bioRxiv : the preprint server for biology (2024)
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Joseph D Deak, Hang Zhou, Marco Galimberti, Daniel F Levey, Frank R Wendt, Sandra Sanchez-Roige, Alexander S Hatoum, Emma C Johnson, Yaira Z Nunez, Ditte Demontis, Anders Dupont Børglum, Veera Manikandan Rajagopal, Mariela V Jennings, Rachel L Kember, Amy C Justice, Howard J Edenberg, Arpana Agrawal, Renato Polimanti, Henry R Kranzler, Joshua C Gray
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci. Molecular psychiatry 27 (10) (2022)
Anurag Verma, Scott M Damrauer, Nawar Naseer, JoEllen Weaver, Colleen M Kripke, Lindsay Guare, Giorgio Sirugo, Rachel L Kember, Theodore G Drivas, Scott M Dudek, Yuki Bradford, Anastasia Lucas, Renae Judy, Shefali S Verma, Emma A Meagher, Katherine L Nathanson, Michael D Feldman, Marylyn D Ritchie, Daniel James Rader, null For The Penn Medicine BioBank
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population. Journal of personalized medicine 12 (12) (2022)
Catherine Tcheandjieu, Ke Xiao, Helio Tejeda, Julie A Lynch, Sanni E Ruotsalainen, Tiffany Bellomo, Madhuri Palnati, Renae Judy, Derek M Klarin, Rachel L Kember, Shefali Verma, null null, null null, null null, Aarno Palotie, Mark Daly, Marylyn DeRiggi Ritchie, Daniel James Rader, Manuel A Rivas, Themistocles L Assimes, Philip Tsao, Scott Damrauer, James R Priest
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease. Nature genetics 54 (6) (2022)
Henry R Kranzler, Hang Zhou, Rachel L Kember
Identifying and Reducing Bias in Genome-Wide Association Studies of Alcohol-Related Traits. The American journal of psychiatry 179 (1) (2022)
Anurag Verma, Scott M Damrauer, Nawar Naseer, JoEllen Weaver, Colleen M Kripke, Lindsay Guare, Giorgio Sirugo, Rachel L Kember, Theodore G Drivas, Scott M Dudek, Yuki Bradford, Anastasia Lucas, Renae Judy, Shefali S Verma, Emma A Meagher, Katherine L Nathanson, Michael D Feldman, Marylyn D Ritchie, Daniel James Rader, null For The Penn Medicine BioBank
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population. Journal of personalized medicine 12 (12) (2022)
Sylvanus Toikumo, Heng Xu, Joshua C Gray, Rachel L Kember, Henry R Kranzler
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47 (13) (2022)
Tiffany Love, Andrey A Shabalin, Rachel L Kember, Anna R Docherty, Hang Zhou, Vincent Koppelmans, Joshua C Gray, Anne K Baker, Emily E Hartwell, Jacob Dubroff, Jon-Kar Zubieta, Henry R Kranzler
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47 (10) (2022)
Anurag Verma, Scott M Damrauer, Nawar Naseer, JoEllen Weaver, Colleen M Kripke, Lindsay Guare, Giorgio Sirugo, Rachel L Kember, Theodore G Drivas, Scott M Dudek, Yuki Bradford, Anastasia Lucas, Renae Judy, Shefali S Verma, Emma A Meagher, Katherine L Nathanson, Michael D Feldman, Marylyn D Ritchie, Daniel James Rader, null For The Penn Medicine BioBank
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population. Journal of personalized medicine 12 (12) (2022)
Richard Karlsson Linnér, Travis T Mallard, Peter B Barr, Sandra Sanchez-Roige, James W Madole, Morgan N Driver, Holly E Poore, Ronald de Vlaming, Andrew D Grotzinger, Jorim J Tielbeek, Emma C Johnson, Mengzhen Liu, Sara Brin Rosenthal, Trey Ideker, Hang Zhou, Rachel L Kember, Joëlle A Pasman, Karin J H Verweij, Dajiang J Liu, Scott I Vrieze, null null, Henry R Kranzler, Joshua C Gray, Kathleen Mullan Harris, Elliot M Tucker-Drob, Irwin D Waldman, Abraham A Palmer, Kathryn Paige Harden, Philipp D Koellinger, Danielle M Dick
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nature neuroscience 24 (10) (2021)
Sarah E Graham, Shoa L Clarke, Kuan-Han H Wu, Stavroula Kanoni, Gregory J M Zajac, Shweta Ramdas, Ida Surakka, Ioanna Ntalla, Sailaja Vedantam, Thomas W Winkler, Adam E Locke, Eirini Marouli, Mi Yeong Hwang, Sohee Han, Akira Narita, Ananyo Choudhury, Amy R Bentley, Kenneth Ekoru, Anurag Verma, Bhavi Trivedi, Hilary C Martin, Karen A Hunt, Qin Hui, Derek Klarin, Xiang Zhu, Gudmar Thorleifsson, Anna Helgadottir, Daníel F Guðbjartsson, Hilma Hólm, Isleifur Olafsson, Masato Akiyama, Saori Sakaue, Chikashi C Terao, Masahiro Kanai, Wei Zhou, Ben Michael Brumpton, Humaira Rasheed, Sanni E Ruotsalainen, Aki S Havulinna, Yogasudha Veturi, QiPing Feng, Elisabeth A Rosenthal, Todd Lingren, Jennifer Allen Pacheco, Sarah A Pendergrass, Jeffrey Haessler, Franco Giulianini, Yuki Bradford, Jason E Miller, Archie I Campbell, Kuang Lin, Iona Y Millwood, George Hindy, Asif Rasheed, Jessica D Faul, Wei Zhao, David R Weir, Constance Turman, Hongyan Huang, Mariaelisa Graff, Anubha Mahajan, Michael R Brown, Weihua Zhang, Ketian Yu, Ellen M Schmidt, Anita Pandit, Stefan Gustafsson, Xianyong Yin, Jian'an Luan, Jing-Hua Zhao, Fumihiko Matsuda, Hye-Mi Jang, Kyungheon Yoon, Carolina Medina-Gomez, Achilleas Pitsillides, Jouke- Jan Hottenga, Gonneke Willemsen, Andrew R Wood, Yingji Ji, Zishan Gao, Simown Howarth, Ruth E Mitchell, Jin Fang Chai, Mette Aadahl, Jie Yao, Ani Manichaikul, Helen R Warren, Julia Ramírez, Jette Bork-Jensen, Line L Kårhus, Anuj Goel, Maria Sabater-Lleal, Raymond Noordam, Carlo Sidore, Edoardo Fiorillo, Aaron F McDaid, Pedro-Manuel Marques-Vidal, Matthias Wielscher, Stella Trompet, Naveed Sattar, Line T Møllehave, Betina H Thuesen, Matthias Munz, Lingyao Zeng, Jianfeng Huang, Bin Yang, Alaitz Poveda, Azra Kurbasic, Claudia Lamina, Lukas Forer, Markus Scholz, Tessel E Galesloot, Jonathan P Bradfield, E Warwick Daw, Joseph M Zmuda, Jonathan S Mitchell, Christian Fuchsberger, Henry Christensen, Jennifer A Brody, Mary F Feitosa, Mary K Wojczynski, Michael H Preuss, Massimo Mangino, Paraskevi Christofidou, Niek Verweij, Jan W Benjamins, Jorgen Engmann, Rachel L Kember, Roderick C Slieker, Ken Sin Lo, Nuno R Zilhao, Phuong Le, Marcus E Kleber, Graciela E Delgado, Shaofeng Huo, Daisuke D Ikeda, Hiroyuki Iha, Jian Yang, Jun Liu, Hampton L Leonard, Jonathan Marten, Börge Schmidt, Marina Arendt, Laura Jane Smyth, Marisa Cañadas-Garre, Chaolong Wang, Masahiro Nakatochi, Andrew Wong, Nina Hutri-Kähönen, Xueling S Sim, Rui Xia, Alicia Huerta-Chagoya, Juan Carlos Fernandez López, Valeriya Lyssenko, Meraj Ahmed, Anne U Jackson, Marguerite R Irvin, Christopher Oldmeadow, Han-Na Kim, Seungho Ryu, Paul R H J Timmers, Liubov Arbeeva, Rajkumar Dorajoo, Leslie A Lange, Xiaoran Chai, Gauri Prasad, Laura Lorés-Motta, Marc Pauper, Jirong Long, Xiaohui Li, Elizabeth Theusch, Fumihiko Takeuchi, Cassandra N Spracklen, Anu Loukola, Sailalitha Bollepalli, Sophie C Warner, Ya Xing Wang, Wen B Wei, Teresa Nutile, Daniela Ruggiero, Yun Ju Sung, Yi-Jen Hung, Shufeng Chen, Fangchao Liu, Jingyun Yang, Katherine A Kentistou, Mathias Gorski, Marco Brumat, Karina Meidtner, Lawrence F Bielak, Jennifer A Smith, Prashantha Hebbar, Aliki-Eleni Farmaki, Edith Hofer, Maoxuan Lin, Chao Xue, Jifeng Zhang, Maria Pina Concas, Simona Vaccargiu, Peter J van der Most, Niina Pitkänen, Brian E Cade, Jiwon Lee, Sander W van der Laan, Kumaraswamy Naidu Chitrala, Stefan Weiss, Martina E Zimmermann, Jong Young Lee, Hyeok Sun Choi, Maria Nethander, Sandra Freitag-Wolf, Lorraine Southam, Nigel W Rayner, Carol A Wang, Shih-Yi Lin, Jun-Sing Wang, Christian Couture, Leo-Pekka Lyytikäinen, Kjell C Nikus, Gabriel Cuellar-Partida, Henrik Vestergaard, Bertha Hildalgo, Olga Giannakopoulou, Qiuyin Cai, Morgan O Obura, Jessica van Setten, Xiaoyin Li, Karen Schwander, Natalie Terzikhan, Jae Hun Shin, Rebecca D Jackson, Alexander P Reiner, Lisa Warsinger Martin, Zhengming Chen, Liming Li, Heather M Highland, Kristin L Young, Takahisa Kawaguchi, Joachim Thiery, Joshua C Bis, Girish N Nadkarni, Lenore J Launer, Huaixing Li, Mike A Nalls, Olli T Raitakari, Sahoko Ichihara, Sarah D Wild, Christopher P Nelson, Harry Campbell, Susanne Jäger, Toru Nabika, Fahd Al-Mulla, Harri Niinikoski, Peter S Braund, Ivana Kolcic, Peter Kovacs, Tota Giardoglou, Tomohiro Katsuya, Konain Fatima Bhatti, Dominique de Kleijn, Gert J de Borst, Eung Kweon Kim, Hieab H H Adams, M Arfan Ikram, Xiaofeng Zhu, Folkert W. Asselbergs, Adriaan O Kraaijeveld, Joline W J Beulens, Xiao-Ou Shu, Loukianos S Rallidis, Oluf Pedersen, Torben Hansen, Paul Mitchell, Alex W Hewitt, Mika Kähönen, Louis Perusse, Claude Bouchard, Anke Tönjes, Yii-Der Ida Chen, Craig E Pennell, Trevor A Mori, Wolfgang Lieb, Andre Franke, Claes Ohlsson, Dan Mellström, Yoon Shin Cho, Hyejin Lee, Jian-Min Yuan, Woon-Puay Koh, Sang Youl Rhee, Jeong-Taek Woo, Iris M Heid, Klaus J Stark, Henry Völzke, Georg Homuth, Michele K Evans, Alan B Zonderman, Ozren Polasek, Gerard Pasterkamp, Imo E Hoefer, Susan Redline, Katja Pahkala, Albertine J Oldehinkel, Harold Snieder, Ginevra Biino, Reinhold Schmidt, Helena Schmidt, Y Eugene Chen, Stefania Bandinelli, George Dedoussis, Thangavel Alphonse Thanaraj, Sharon L R Kardia, Norihiro Kato, Matthias B Schulze, Giorgia Girotto, Bettina Jung, Carsten A Böger, Peter K Joshi, David A Bennett, Philip Lawrence De Jager, Xiangfeng Lu, Vasiliki Mamakou, Morris Brown, Mark J Caulfield, Patricia B Munroe, Xiuqing Guo, Marina Ciullo, Jost Bruno Jonas, Nilesh J Samani, Jaakko A Kaprio, Päivi Pajukanta, Linda S Adair, Sonny Augustin Bechayda, H Janaka de Silva, Ananda R Wickremasinghe, Ronald M Krauss, Jer-Yuarn Wu, Wei Zheng, Anneke I den Hollander, Dwaipayan Bharadwaj, Adolfo Correa, James F Wilson, Lars Lind, Chew-Kiat Heng, Amanda E Nelson, Yvonne M Golightly, James F Wilson, Brenda Penninx, Hyung-Lae Kim, John Attia, Rodney J Scott, D C Rao, Donna K Arnett, Mark Walker, Heikki A Koistinen, Giriraj Ratan Chandak, Chittaranjan S Yajnik, Josep Maria Mercader, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Clicerio Gonzalez Villalpando, Lorena Orozco-Orozco, Myriam Fornage, E Shyong Tai, Rob M van Dam, Terho Lehtimäki, Nish Chaturvedi, Mitsuhiro Yokota, Jian-Jun Liu, Dermot F Reilly, Amy Jayne McKnight, Frank Kee, Karl-Heinz Jöckel, Mark I McCarthy, Colin N A Palmer, Veronique Vitart, Caroline Hayward, Eleanor Simonsick, Cornelia M van Duijn, Fan Lu, Jia Qu, Haretsugu Hishigaki, Xu Lin, Winfried März, Esteban J Parra, Miguel Cruz, Vilmundur Gudnason, Jean-Claude Tardif, Guillaume Lettre, Leen M 't Hart, Petra J M Elders, Scott M Damrauer, Meena Kumari, Mika Kivimaki, Pim van der Harst, Timothy D Spector, Ruth J F Loos, Michael A Province, Bruce M Psaty, Ivan Brandslund, Peter P Pramstaller, Kaare Christensen, Samuli Ripatti, Elisabeth Widén, Hakon H Hakonarson, Struan F A Grant, Lambertus A L M Kiemeney, Jacqueline de Graaf, Markus Loeffler, Florian Kronenberg, Dongfeng Gu, Jeanette Erdmann, Heribert Schunkert, Paul W Franks, Allan Linneberg, Johan Wouter Jukema, Amit V Khera, Minna Männikkö, Marjo-Riitta Jarvelin, Zoltan Kutalik, Francesco Cucca, Dennis O Mook-Kanamori, Ko Willems van Dijk, Hugh Watkins, David P Strachan, Niels Grarup, Peter Sever, Neil Poulter, Jerome I Rotter, Thomas M Dantoft, Fredrik Karpe, Matt J Neville, Nicholas J Timpson, Ching-Yu Cheng, Tien-Yin Wong, Chiea Chuen Khor, Sabanayagam Charumathi, Annette Peters, Christian Gieger, Andrew T Hattersley, Nancy L Pedersen, Patrik K E Magnusson, Dorret I Boomsma, Eco J C N de Geus, L Adrienne Cupples, Joyce B J van Meurs, Mohsen Ghanbari, Penny Gordon-Larsen, Wei Huang, Young Jin Kim, Yasuharu Tabara, Nicholas J Wareham, Claudia Langenberg, Eleftheria Zeggini, Johanna Kuusisto, Markku Laakso, Erik Ingelsson, Goncalo Abecasis, John C Chambers, Jaspal S Kooner, Paul S de Vries, Alanna C Morrison, Kari E North, Martha Daviglus, Peter Kraft, Nicholas G Martin, John B Whitfield, Shahid Abbas, Danish Saleheen, Robin G Walters, Michael V Holmes, Corri Black, Blair Hamilton Smith, Anne E Justice, Aris Baras, Julie E Buring, Paul M Ridker, Daniel I Chasman, Charles Kooperberg, Wei-Qi Wei, Gail P Jarvik, Bahram Namjou, M Geoffrey Hayes, Marylyn D Ritchie, Pekka Jousilahti, Veikko V Salomaa, Kristian Hveem, Bjørn Olav Åsvold, Michiaki Kubo, Yoichiro Kamatani, Yukinori Okada, Yoshinori Murakami, Unnur Thorsteinsdottir, Kari Stefansson, Yuk-Lam Ho, Julie A Lynch, Daniel J Rader, Philip S Tsao, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, John M Gaziano, Peter Wilson, Charles N Rotimi, Scott Hazelhurst, Michelle Ramsay, Richard C Trembath, David A van Heel, Gen Tamiya, Masayuki Yamamoto, Bong-Jo Kim, Karen L Mohlke, Timothy M Frayling, Joel N Hirschhorn, Sekar Kathiresan, null null, null null, Michael Boehnke, Pradeep Natarajan, Gina M Peloso, Christopher D Brown, Andrew P Morris, Themistocles L Assimes, Panagiotis Deloukas, Yan V Sun, Cristen J Willer
The power of genetic diversity in genome-wide association studies of lipids. Nature (2021)
Kelly Finke, Michael Kourakos, Gabriela Brown, Huyen Trang Dang, Shi Jie Samuel Tan, Yuval B Simons, Shweta Ramdas, Alejandro A Schäffer, Rachel L Kember, Maja Bućan, Sara Mathieson
Ancestral haplotype reconstruction in endogamous populations using identity-by-descent. PLoS computational biology 17 (2) (2021)
Xiangchen Gu, Hongliu Yang, Xin Sheng, Yi-An Ko, Chengxiang Qiu, Jiwhan Park, Shizheng Huang, Rachel L Kember, Renae L Judy, Joseph Park, Scott M Damrauer, Girish Nadkarni, Ruth J F Loos, Ha My Thi Vy, Kumardeep Chaudhary, Erwin P Böttinger, Ishan Paranjpe, Aparna Saha, Christopher D Brown, Shreeram Akilesh, Adriana M Hung, Matthew Palmer, Aris Baras, John D Overton, Jeffrey G Reid, Marylyn DeRiggi Ritchie, Daniel J Rader, Katalin Suszták
Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity. Science translational medicine 13 (576) (2021)
Emma C Johnson, Manav Kapoor, Alexander S Hatoum, Hang Zhou, Renato Polimanti, Frank R Wendt, Raymond K Walters, Dongbing Lai, Rachel L Kember, Sarah M Hartz, Jacquelyn M Meyers, Roseann E Peterson, Stephan Ripke, Tim B Bigdeli, Ayman H Fanous, Carlos N Pato, Michele T Pato, Alison Mary Goate, Henry R Kranzler, Michael C O'Donovan, James T R Walters, Joshua C Gray, Howard J Edenberg, Arpana Agrawal
Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder. Psychological medicine (2021)
Emily E Hartwell, Alison K Merikangas, Shefali Setia Verma, Marylyn DeRiggi Ritchie, null null, Henry R Kranzler, Rachel L Kember
Genetic liability for substance use associated with medical comorbidities in electronic health records of African- and European-ancestry individuals. Addiction biology (2021)
Cecilia Dao, Hang Zhou, Aeron M Small, Kirsha S Gordon, Boyang Li, Rachel L Kember, Yixuan Ye, Joshua C Gray, Ke Xu, Henry R Kranzler, Hongyu Zhao, Amy C Justice
The impact of removing former drinkers from genome-wide association studies of AUDIT-C. Addiction (Abingdon, England) 116 (11) (2021)
Nicole M Ferraro, Benjamin J Strober, Jonah Einson, Nathan S Abell, François Aguet, Alvaro N Barbeira, Margot Brandt, Maja Bucan, Stephane E Castel, Joe R Davis, Emily Greenwald, Gaelen T Hess, Austin T Hilliard, Rachel L Kember, Bence Kotis, YoSon Park, Gina Peloso, Shweta Ramdas, Alexandra J Scott, Craig Smail, Emily K Tsang, Seyedeh Maryam Zekavat, Marcello Ziosi, null Aradhana, null null, Kristin G Ardlie, Themistocles L Assimes, Michael C Bassik, Christopher D Brown, Adolfo Correa, Ira Hall, Hae Kyung Im, Xin Li, Pradeep Natarajan, null null, Tuuli Lappalainen, Pejman Mohammadi, Stephen B Montgomery, Alexis J Battle
Transcriptomic signatures across human tissues identify functional rare genetic variation. Science (New York, N.Y.) 369 (6509) (2020)
Joseph Park, Michael G Levin, Christopher M Haggerty, Dustin N Hartzel, Renae Judy, Rachel L Kember, Nosheen Reza, null null, Marylyn D Ritchie, Anjali T Owens, Scott M Damrauer, Daniel James Rader
A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes. Genetics in medicine : official journal of the American College of Medical Genetics 22 (1) (2019)

Rachel L Kember.css-eqlu8i{font-size:small;padding-left:4px;} (Rachel Kember)

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Rachel L Kember (Rachel Kember)