Early Changes in Puffing Intensity When Exclusively Using Open-Label Very Low Nicotine Content Cigarettes.
Cassidy M WhiteClifford H WatsonRoberto Bravo CardenasPhuong NgacLiza Valentin-BlasiniBenjamin C BlountJoseph S KoopmeinersRachel L Denlinger-ApteLauren R PacekNeal L BenowitzDorothy K HatsukamiEric C DonnyMatthew J CarpenterTracy T SmithPublished in: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2022)
In an environment where no other sources of nicotine are available, people who smoke daily may initially attempt to compensate for cigarette nicotine reduction by puffing on individual cigarettes with greater intensity. Ultimately, the compensatory behavior changes required to achieve usual nicotine intake from VLNC cigarettes are drastic and unrealistic. Accordingly, people are unlikely to sustain attempts to compensate for very low cigarette nicotine content.