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Long-term Efficacy and Safety of Tonic Motor Activation (TOMAC) for Treatment of Medication-Refractory Restless Legs Syndrome: A 24-Week Open-label Extension Study.

Asim RoyJoseph OjileJerrold KramJonathan OlinRussell RosenbergJ Douglas HudsonRichard K BoganJonathan D Charlesworth
Published in: Sleep (2023)
TOMAC remained safe and efficacious for >24 total weeks of treatment with partial reversion of benefits upon cessation.
Keyphrases
  • open label
  • clinical trial
  • randomized controlled trial
  • emergency department
  • combination therapy
  • case report
  • study protocol
  • electronic health record