DXA-based Fat Mass With Risk of Worsening Insulin Resistance in Adolescents: A 9-Year Temporal and Mediation Study.
Andrew O AgbajeChristoph SanerJie ZhangMélanie HendersonTomi-Pekka TuomainenPublished in: The Journal of clinical endocrinology and metabolism (2024)
Mid-adolescence may be an optimal time for interrupting the worsening fat mass-insulin resistance pathologic cycle and attenuating the risk of progressively worsening metabolic dysfunction before young adulthood.
Keyphrases
- adipose tissue
- insulin resistance
- depressive symptoms
- young adults
- physical activity
- type diabetes
- body composition
- oxidative stress
- high fat diet
- fatty acid
- neoadjuvant chemotherapy
- magnetic resonance imaging
- middle aged
- polycystic ovary syndrome
- skeletal muscle
- computed tomography
- magnetic resonance
- lymph node
- early life
- postmenopausal women