Effects of Circulating HMGB-1 and Histones on Cardiomyocytes-Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma.
Birte WeberIna LacknerMeike BaurGiorgio FoisFlorian GebhardIngo MarziHubert SchrezenmeierBorna ReljaMiriam KalbitzPublished in: Journal of clinical medicine (2020)
Danger associated molecular patterns such as HMGB-1 and extracellular histones impair human CM in vitro. A hemadsorption filter could be a therapeutic option to reduce high concentrations of histones.