Serum neurofilament light chain is a useful biomarker in pediatric multiple sclerosis.
Marie-Christine ReinertPascal BenkertJens WuerfelZuzanna MichalakEsther RuberteChristian BarroPeter HuppkeWiebke StarkHarald KropshoferDavorka TomicDavid LeppertJens KuhleWolfgang BrückJutta GärtnerPublished in: Neurology(R) neuroimmunology & neuroinflammation (2020)
sNfL is a useful biomarker for monitoring disease activity and treatment response in pediatric MS. It is most likely helpful to predict disease severity and to guide treatment decisions in patients with pediatric MS. This study provides Class III evidence that sNfL levels are associated with disease activity in pediatric MS.