Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.
Zoe WintersJ HorsnellK T ElversA J MaxwellL J JonesA M ShaabanP SchmidNorman R WilliamsA BeswickR GreenwoodJ C IngramC SaundersJayant S VaidyaL EssermanI JatoiA M BruntPublished in: BJS open (2018)
The available studies were mainly of moderate quality, historical and underpowered, with limited follow-up and biased case selection favouring BCS rather than mastectomy for low-risk patients. The evidence was inconclusive, weakening support for the St Gallen consensus and supporting a future randomized trial.
Keyphrases
- systematic review
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- minimally invasive
- meta analyses
- papillary thyroid
- prognostic factors
- coronary artery bypass
- randomized controlled trial
- type diabetes
- squamous cell carcinoma
- high intensity
- patient reported outcomes
- metabolic syndrome
- current status
- young adults
- insulin resistance
- squamous cell
- radiation therapy
- adipose tissue
- lymph node
- percutaneous coronary intervention
- lymph node metastasis
- early breast cancer