Oral health-related quality of life in oral cancer patients: systematic review and meta-analysis.
Monal B YuwanatiShailesh M GondivkarSachin Chakradhar SarodeAmol Ramchandra GadbailAmi DesaiShubhangi MhaskeSandeep K PathakMahalaqua Nazli KhatibPublished in: Future oncology (London, England) (2021)
Aim: The purpose of this meta-analysis was to evaluate the impact of oral health on quality of life in oral cancer patients (OCPs). Methods: PubMed, Scopus and Web of Science databases were searched for publications on oral health-related quality of life (OHRQoL) in OCP and the information was extracted according to the PRISMA guidelines. A random effect model was used to obtain the pooled standard mean differences of Oral Health Impact Profile (OHIP)-14 questionnaire responses in meta-analysis. Results: total of 12 research papers were analyzed and revealed poor OHRQoL in OCPs (standard mean difference: 2.53; 95% CI: 1.55-3.50; p < 0.00001) compared with healthy individuals due to the effects of oncotherapy. Moreover, OHRQoL deteriorated with combinations of different treatment modalities. Conclusion: Oral health and oncotherapy can affect the quality of life in OCPs.
Keyphrases
- oral health
- systematic review
- meta analyses
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- public health
- case control
- prognostic factors
- randomized controlled trial
- healthcare
- clinical trial
- patient reported outcomes
- machine learning
- clinical practice
- psychometric properties
- health information
- combination therapy
- social media
- phase iii