5S rRNA pseudogene transcripts are associated with interferon production and inflammatory responses in alcohol-associated hepatitis.

Jianguo Wu Adam Kim Xiaoqin Wu Semanti RayDaniela S AllendeNicole WelchAnnette BellarJaividhya DasarathySrinivasan Dasarathy Laura E Nagy

Published in: Hepatology (Baltimore, Md.) (2023)

Increased expression and binding availability of RNA5SP transcripts was associated with hepatic IFN production and inflammation in sAH. These data identify RNA5SP transcripts as a potential target to mitigate inflammation and hepatocellular injury in AH.

Keyphrases

oxidative stress
dendritic cells
poor prognosis
immune response
nucleic acid
big data
human health
risk assessment
long non coding rna
data analysis