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Beneficial effects of troxerutin on metabolic disorders in non-obese model of metabolic syndrome.

Hana MalinskaMartina HüttlOlena OliyarnykIrena MarkovaMartin PorubaZuzana RacovaLudmila KazdovaRostislav Vecera
Published in: PloS one (2019)
Our results indicate that TRX improves hepatic lipid metabolism and insulin sensitivity in peripheral tissues. As well as ameliorating oxidative stress, TRX can reduce ectopic lipid deposition, affect genes involved in lipid metabolism, and influence the activity of CYP family enzymes.
Keyphrases
  • metabolic syndrome
  • oxidative stress
  • fatty acid
  • insulin resistance
  • uric acid
  • gene expression
  • adipose tissue
  • type diabetes
  • cardiovascular risk factors
  • induced apoptosis
  • chemotherapy induced
  • skeletal muscle