Is the Pannexin-1 Channel a Mechanism Underlying Hypertension in Humans? a Translational Study of Human Hypertension.

Lasse Gliemann Andrea Tamariz-Ellemann Camilla Collin HansenThomas Svare EhlersSophie Møller Ylva Hellsten

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

Contrary to our hypothesis, the data demonstrate that pannexin-1 does not contribute to the elevated blood pressure in essential hypertension, a finding, which also opposes that reported in preclinical models.

Keyphrases

blood pressure
hypertensive patients
heart rate
endothelial cells
electronic health record
blood glucose
stem cells
machine learning
big data
adipose tissue
mesenchymal stem cells
cell therapy
weight loss
artificial intelligence
pluripotent stem cells