Recombinant anti-Müllerian hormone in the maturation medium improves the in vitro maturation of human immature (GV) oocytes after controlled ovarian hormonal stimulation.

Jure BedenkTadeja ReženTaja Železnik RamutaNina JančarEda Vrtačnik BokalKsenija GeršakIrma Virant Klun

Published in: Reproductive biology and endocrinology : RB&E (2022)

The positive AMHR2 protein and AMHR2 gene expression in human oocytes shows that AMH could directly act on human oocytes. This was further functionally confirmed by the IVM procedure. These findings suggest the potential clinical application of recombinant AMH to improve IVM of human oocytes in the future.

Keyphrases

endothelial cells
gene expression
induced pluripotent stem cells
pluripotent stem cells
adipose tissue
minimally invasive
risk assessment
skeletal muscle
climate change
polycystic ovary syndrome
binding protein