Altered proportion of CCR2+ and CX3CR1+ circulating monocytes in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

Yousif SubhiMarie Krogh NielsenChristopher R MolbechTorben L Sørensen

Published in: Clinical & experimental ophthalmology (2018)

Neovascular AMD is associated with increased expression of angiogenesis-associated chemokine receptors in the pro-inflammatory non-classical monocytes. PCV differs from neovascular AMD immunologically and show immunological heterogeneity across angiographic subtypes.

Keyphrases

age related macular degeneration
dendritic cells
poor prognosis
peripheral blood
endothelial cells
single cell
vascular endothelial growth factor
wound healing
optical coherence tomography