Circulating miRNAs in girls with abdominal obesity: miR-221-3p as a biomarker of response to weight loss interventions.
Ana Ojeda-RodríguezTaís Silveira AssmannLucia Alonso-PedreroMaria Cristina Azcona-SanjulianFermín I MilagroAmelia MartiPublished in: Pediatric obesity (2022)
Bioinformatic analysis evidenced that miR-221-3p participates in several obesity-related pathways, and more interestingly, this miRNA targets several candidate genes to childhood obesity according to DisGeNet database. Thus, miR-221-3p could be used for predicting the response to a multidisciplinary intervention for weight loss in young girls.
Keyphrases
- weight loss
- bariatric surgery
- roux en y gastric bypass
- gastric bypass
- randomized controlled trial
- weight gain
- glycemic control
- physical activity
- obese patients
- metabolic syndrome
- insulin resistance
- type diabetes
- emergency department
- high fat diet induced
- middle aged
- adipose tissue
- quality improvement
- body mass index