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Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.

Yiyi MaJack L FollisCaren E SmithToshiko TanakaAni W ManichaikulAudrey Y ChuCecilia SamieriXia ZhouWeihua GuanLu WangMary L BiggsYii-Der I ChenDena G HernandezIngrid BoreckiDaniel I ChasmanStephen S RichLuigi FerrucciMarguerite Ryan IrvinStella AslibekyanDegui ZhiHemant K TiwariSteven A ClaasJin ShaEdmond K KabagambeChao-Qiang LaiLaurence D ParnellYu-Chi LeePhilippe AmouyelJean-Charles LambertBruce M PsatyIrena B KingDariush MozaffarianBarbara McKnightStefania BandinelliMichael Y TsaiPaul M RidkerJingzhong DingKurt Lohmant MstatYongmei LiuNona SotoodehniaPascale Barberger-GateauLyn M SteffenDavid S SiscovickDevin AbsherDonna K ArnettJosé M OrdovásRozenn N Lemaitre
Published in: The American journal of clinical nutrition (2016)
We obtained little evidence that the gene-by-fatty acid interactions on blood lipids act through DNA methylation.
Keyphrases
  • fatty acid
  • dna methylation
  • genome wide
  • copy number
  • case control
  • gene expression
  • heart failure
  • risk factors
  • atrial fibrillation
  • genome wide identification