Ghrelin enhances cisplatin sensitivity in HO-8910 PM human ovarian cancer cells.

Yun LengCan ZhaoGuoliang YanShuangyue XuYinggui YangTing GongXin LiCheng-Lin Li

Published in: Journal of ovarian research (2021)

This study revealed a specifically inhibitory effect of ghrelin on platinum-resistance via suppressing p-P38 and subsequently promoting p-CDK1 mediated cell cycle arrest in HO-8910 PM.

Keyphrases

cell cycle arrest
pi k akt
particulate matter
air pollution
signaling pathway
cell death
endothelial cells
polycyclic aromatic hydrocarbons
heavy metals
cell cycle
cell proliferation
single cell
water soluble
induced pluripotent stem cells
pluripotent stem cells
risk assessment