Comparison of antithrombotic strategies in patients with cryptogenic stroke and patent foramen ovale: an updated meta-analysis.

Filippo AngeliniFederico FortuniGeorgios TsivgoulisGiancarlo AgnelliPier Paolo BocchinoLuca FranchinOvidio De FilippoMatteo BellettiniFabrizio D'AscenzoGabriele CrimiSergio LeonardiGaetano M De FerrariMaurizio Paciaroni

Published in: Cardiovascular drugs and therapy (2020)

OAC was more effective than APT in reducing the risk of stroke recurrence in patients with PFO and CS, without a significant increase in the risk of major bleedings. Our findings support the need for further randomized data focused on the comparison of antithrombotic strategies in this setting.

Keyphrases

atrial fibrillation
systematic review
double blind
open label
electronic health record
meta analyses
randomized controlled trial
clinical trial
phase iii
machine learning
phase ii
clinical evaluation
data analysis