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Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage.

Juan SunYan ZhangJianfei LuWeiguang ZhangJunhao YanLei YangChangman ZhouRenyu LiuChunhua Chen
Published in: Microcirculation (New York, N.Y. : 1994) (2019)
Salvinorin A attenuated CVS and alleviated brain injury after SAH via increasing expression of eNOS and NO content, and decreasing ET-1 concentration and AQP-4 protein expression.
Keyphrases
  • subarachnoid hemorrhage
  • nitric oxide synthase
  • brain injury
  • nitric oxide
  • cerebral ischemia
  • poor prognosis
  • endothelial cells
  • mouse model
  • long non coding rna