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Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive behavior in Prader-Willi syndrome.

Juliette SallesSanaa EddirySaber AmriMélissa GalindoEmmanuelle LacassagneSimon GeorgeXavier MialheÉmeline LhuillierNicolas FranchittoFreddy JeanneteauIsabelle GenneroJean Pierre SallesMaïthé Tauber
Published in: Molecular psychiatry (2024)
SNORD116 MD dopaminergic neurons displayed differential methylation and expression in the COMT and SLC6A3 genes, which are related to dopaminergic clearance.
Keyphrases
  • dna methylation
  • genome wide
  • spinal cord
  • poor prognosis
  • growth hormone
  • gene expression
  • molecular dynamics
  • copy number
  • spinal cord injury
  • long non coding rna
  • induced pluripotent stem cells
  • transcription factor