Effect of Individual Patient Characteristics and Treatment Choices on Reliever Medication Use in Moderate-Severe Asthma: A Poisson Analysis of Randomised Clinical Trials.
Sven C van DijkmanArzu YorgancıoğluIan PavordGuy BrussellePaulo M PitrezSean OosterholtSourabh FumaliAnurita MajumdarOscar Della PasquaPublished in: Advances in therapy (2024)
The availability of individual-level patient data in conjunction with a parametric approach enabled the characterisation of interindividual differences in the patterns of reliever use in patients with moderate-severe asthma. Taken together, individual demographic and clinical characteristics, as well as exacerbation history, can be considered an indicator of the degree of asthma control. High SABA reliever use suggests suboptimal clinical management of patients on maintenance therapy.
Keyphrases
- clinical trial
- chronic obstructive pulmonary disease
- case report
- high intensity
- open label
- lung function
- double blind
- big data
- study protocol
- phase ii
- electronic health record
- randomized controlled trial
- mesenchymal stem cells
- air pollution
- extracorporeal membrane oxygenation
- smoking cessation
- replacement therapy
- allergic rhinitis
- respiratory failure
- mechanical ventilation