Activin levels correlate with lymphocytic infiltration in epithelial ovarian cancer.
Elizabeth T EvansEmily F PageAlex Seok ChoiZainab ShonibareAndrea G KahnRebecca C ArendKarthikeyan MythreyePublished in: Cancer medicine (2024)
INHBA expression is elevated within EOC, correlating with worse survival, with activin protein levels correlating with specific immune infiltration. Our findings suggest that activin-A may play a role in suppressing anti-tumor immunity in EOC, highlighting its potential as a therapeutic target.