Clinical utility of DNA methylation profiling for choroid plexus tumors.

Kee Kiat YeoCassie B MacraeBradley GampelJared T AhrendsenHart LidovKaren D WrightSusan ChiKatie FehnelLissa BairdJessica ClymerKenneth D Aldape Sanda Alexandrescu

Published in: Neuro-oncology advances (2024)

Results indicated that methylation profiling may serve as a valuable tool in the clinical decision-making process for patients with CPTs, providing additional prognostic information compared to WHO histologic grade alone. The value of methylation array analysis is particularly important given the lack of consensus on treatment regimens for CPTs.

Keyphrases

dna methylation
genome wide
decision making
single cell
gene expression
high resolution
high throughput
ultrasound guided
copy number
clinical practice
healthcare
replacement therapy
combination therapy