Heterogeneity of sensitization profiles and clinical phenotypes among patients with seasonal allergic rhinitis in Southern European countries-The @IT.2020 multicenter study.
Stephanie DramburgU GrittnerE PotapovaA TravagliniS TripodiS ArasiS PelosiA Acar ŞahinX AggelidisA BarbalaceA BourgoinB BreguM A BrighettiE CaeiroS Caglayan SozmenL CaminitiD CharpinM CoutoL DelgadoA Di Rienzo BusincoC DimierM V DimouJ A FonsecaOzlem GokselD HernandezC J Hernandez ToroT M HoffmannD T JangF KalpakliogluB LameR LlusarM MakrisÁngel Mazón RamosE MesonjesiA NietoA B ÖztürkL PahusG PajnoI PanasitiPapadopoulos G NikolaosE PellegriniAna Margarida PereiraM PereiraN M PinarA PriftanjiF PsarrosCansin SackesenI SfikaJ SuarezM ThibaudonU UguzV VerdierV VillellaParaskevi XepapadakiD YaziciPaolo Maria MatricardiPublished in: Allergy (2024)
In Southern European countries, pollen allergy is heterogeneous in terms of sensitization profiles and clinical manifestations. Despite the complexity, a unique molecular, multiplex, and customized in-vitro IgE test detected relevant sensitization in all study centers. Nevertheless, this geographical diversity in pollen allergic patients imposes localized clinical guidelines and study protocols for clinical trials of SAR in this climatically complex region.