Longitudinal non-adherence predicts treatment escalation in paediatric ulcerative colitis.

Julia K CarmodyJill PlevinskyJames L PeughLee A DensonJeffrey S HyamsDebra LobatoNeal S LeLeikoKevin A Hommel

Published in: Alimentary pharmacology & therapeutics (2019)

Non-adherence may have affected therapeutic efficacy of standardised mesalazine, thereby contributing to need for treatment escalation. Routine adherence monitoring for at least 6 months following treatment initiation and addressing adherence difficulties early in the disease course are recommended.

Keyphrases

emergency department
intensive care unit
ulcerative colitis
randomized controlled trial
clinical trial
metabolic syndrome
glycemic control
clinical practice
skeletal muscle
replacement therapy
smoking cessation