Multiparametric bone MRI can improve CT-guided bone biopsy target selection in cancer patients and increase diagnostic yield and feasibility of next-generation tumour sequencing.
Ricardo DonnersInes FigueiredoNina TunariuMatthew BlackledgeDow-Mu KohMaria de Los Dolores Fenor de la MazaKhobe ChandranJohann S de BonoNicos FotiadisPublished in: European radiology (2022)
• Multiparametric bone MRI with diffusion-weighted and relative fat-fraction images helps to identify active bone metastases suitable for CT-guided biopsy. • Target lesions for CT-guided bone biopsies in cancer patients can be chosen with greater confidence. • CT-guided bone biopsy success rates, especially yielding sufficient viable tissue for advanced molecular tissue analyses, can be improved.
Keyphrases
- contrast enhanced
- diffusion weighted
- bone mineral density
- magnetic resonance imaging
- computed tomography
- image quality
- dual energy
- magnetic resonance
- soft tissue
- bone loss
- ultrasound guided
- bone regeneration
- diffusion weighted imaging
- adipose tissue
- fine needle aspiration
- body composition
- deep learning
- fatty acid
- single molecule