Risk of hepatitis B virus reactivation with direct-acting antivirals against hepatitis C virus: A cohort study from Egypt and meta-analysis of published data.

Mohamed El Kassas Yusuke ShimakawaZainab Ali-EldinAnna-Louise FunkMohamed Naguib WifiSamy ZakyFathiya El-RaeyGamal EsmatArnaud Fontanet

Published in: Liver international : official journal of the International Association for the Study of the Liver (2018)

We confirmed high HBV reactivation risk in HBsAg-positive patients undergoing DAAs, with only a minority developing clinically important hepatitis. The risk is negligible for HBsAg-negative anti-HBc-positive patients.

Keyphrases

hepatitis b virus
hepatitis c virus
patients undergoing
liver failure
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
human immunodeficiency virus
peritoneal dialysis
systematic review
randomized controlled trial
big data
hiv infected