ZNF703 promotes tumor progression in ovarian cancer by interacting with HE4 and epigenetically regulating PEA15.

Shuang WangCaixia WangYuexin HuXiao LiShan JinOuxuan LiuRui GouYuan ZhuangQian GuoXin NieLiancheng ZhuJuanjuan LiuBei Lin

Published in: Journal of experimental & clinical cancer research : CR (2020)

The results showed that ZNF703 as an oncogene played an important role in the epigenetic modification of ovarian cancer proliferation, and suggested that ZNF703 as a transcription factor may become a prognostic factor and a potential therapeutic target for ovarian cancer.

Keyphrases

prognostic factors
transcription factor
gene expression
poor prognosis
signaling pathway
dna binding
long non coding rna
risk assessment
climate change
human health