PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction.

Lorenzo Da DaltLaura CastiglioniAndrea Baragetti Matteo Audano Monika Svecla Fabrizia Bonacina Silvia PedrettiPatrizia UboldiPatrizia Benzoni Federica Giannetti Andrea Barbuti Fabio Pellegatta Serena Indino Elena Donetti Luigi Sironi Nico Mitro Alberico Luigi Catapano Giuseppe Danilo Norata

Published in: European heart journal (2021)

PCSK9 deficiency impacts cardiac lipid metabolism in an LDLR independent manner and contributes to the development of HFpEF.

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