An update on the development on tubulin inhibitors for the treatment of solid tumors.
Prasanna Anjaneyulu YakkalaShaik RahamanP S Lakshmi SoukyaSajeli Ahil BegumAhmed KamalPublished in: Expert opinion on therapeutic targets (2024)
Microtubules play a crucial role in cellular processes, especially in cancer therapy where inhibiting tubulin polymerization holds promise. Ongoing trials signify a commitment to revolutionizing cancer treatment and exploring targeted therapies. Challenges in microtubule modulation, like resistance and off-target effects, demand focused efforts, emphasizing combination therapies and personalized treatments. Beyond microtubules, promising avenues in cancer research include immunotherapy, genomic medicine, CRISPR gene editing, liquid biopsies, AI diagnostics, and stem cell therapy, showcasing a holistic approach for future advancements.
Keyphrases
- cell therapy
- cancer therapy
- stem cells
- mesenchymal stem cells
- papillary thyroid
- crispr cas
- signaling pathway
- genome wide
- artificial intelligence
- genome editing
- squamous cell
- big data
- copy number
- current status
- gene expression
- ionic liquid
- quality improvement
- squamous cell carcinoma
- deep learning
- childhood cancer
- ultrasound guided
- bone marrow
- replacement therapy