Minimally Invasive Intracerebral Hemorrhage Evacuation Techniques: A Review.
Theodore C HannahRebecca KellnerChristopher P KellnerPublished in: Diagnostics (Basel, Switzerland) (2021)
Intracerebral hemorrhage (ICH) continues to have high morbidity and mortality. Improving ICH outcomes likely requires rapid removal of blood from the parenchyma and restraining edema formation while also limiting further neuronal damage due to the surgical intervention. Minimally invasive surgery (MIS) approaches promise to provide these benefits and have become alluring options for management of ICH. This review describes six MIS techniques for ICH evacuation including craniopuncture, stereotactic aspiration with thrombolysis, endoport-mediated evacuation, endoscope-assisted evacuation, adjunctive aspiration devices, and the surgiscope. The efficacy of each modality is discussed based on current literature. The largest clinical trials have yet to demonstrate definitive effects of MIS intervention on mortality and functional outcomes for ICH. Thus, there is a significant need for further innovation for ICH treatment. Multiple ongoing trials promise to better clarify the potential of the newer, non-thrombolytic MIS techniques.
Keyphrases
- clinical trial
- minimally invasive
- randomized controlled trial
- pulmonary embolism
- brain injury
- systematic review
- oxidative stress
- big data
- acute ischemic stroke
- squamous cell carcinoma
- ultrasound guided
- cardiovascular events
- risk factors
- small cell lung cancer
- cardiovascular disease
- deep learning
- skeletal muscle
- weight loss
- climate change
- robot assisted
- open label
- artificial intelligence
- loop mediated isothermal amplification
- rectal cancer