Login / Signup

Biomechanical properties of breast tissue, a state-of-the-art review.

Nilza G RamiãoPedro Alexandre Lopes de Sousa MartinsRita RynkevicAntónio A FernandesMaria BarrosoDiana C Santos
Published in: Biomechanics and modeling in mechanobiology (2016)
This paper reviews the existing literature on the tests used to determine the mechanical properties of women breast tissues (fat, glandular and tumour tissue) as well as the different values of these properties. The knowledge of the mechanical properties of breast tissue is important for cancer detection, study and planning of surgical procedures such as surgical breast reconstruction using pre-surgical methods and improving the interpretation of clinical tests. Based on the data collected from the analysed studies, some important conclusions were achieved: (1) the Young's modulus of breast tissues is highly dependent on the tissue preload compression level, and (2) the results of these studies clearly indicate a wide variation in moduli not only among different types of tissue but also within each type of tissue. These differences were most evident in normal fat and fibroglandular tissues.
Keyphrases
  • gene expression
  • adipose tissue
  • systematic review
  • squamous cell carcinoma
  • randomized controlled trial
  • pregnant women
  • skeletal muscle
  • label free
  • meta analyses
  • finite element