Involvement of integument-rich CYP4G19 in hydrocarbon biosynthesis and cuticular penetration resistance in Blattella germanica (L.).

Our findings confirm that CYP4G19 is involved in hydrocarbon production and appears to contribute to hydrocarbon-based penetration resistance in B. germanica. This study highlights the lipid-based penetration resistance, advancing our understanding of the molecular mechanism underlying P450-mediated cuticular penetration resistance in insects. © 2019 Society of Chemical Industry.