Anti-cancer effect of targeting fibroblast activation protein alpha in glioblastoma through remodeling macrophage phenotype and suppressing tumor progression.

Yazhou MiaoYuxuan DengJinqiu LiuJing WangBoyi HuShuyu HaoHerui WangZhe ZhangZeping JinYang ZhangChunzhao LiPeng ZhangHong WanShaodong ZhangJie FengNan Ji

Published in: CNS neuroscience & therapeutics (2022)

FAP could serve as a biomarker and novel therapeutic target for the treatment of GBM and that PT100 is a promising drug for the treatment of GBM.

Keyphrases

signaling pathway
emergency department
poor prognosis
combination therapy
long non coding rna
small molecule
amino acid
protein protein
replacement therapy