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Potential role of fructose on human colon DNA methylation in racial disparities observed for colorectal cancer risk.

Matthew A M DevallStephen EatonGaizun HuXiangqing SunEthan JakumSamyukta VenkateshSteven M PowellCynthia YoshidaDaniel J WeisenbergerGregory S CooperJoseph WillisSeham EbrahimJamie ZoellnerGraham CaseyLi Li
Published in: medRxiv : the preprint server for health sciences (2023)
Our mechanistic data support the notion that fructose has a greater CRC-related effect in right than left AA colon, alluding to a potential role for fructose in contributing to racial disparities in CRC.
Keyphrases
  • dna methylation
  • endothelial cells
  • african american
  • gene expression
  • genome wide
  • affordable care act
  • electronic health record
  • induced pluripotent stem cells
  • big data
  • pluripotent stem cells
  • deep learning