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Real-World Usage of Sacubitril/Valsartan in Korea: A Multi-Center, Retrospective Study.

Jin Joo ParkSang-Eun LeeHyun-Jai ChoJin Oh ChoiByung-Su YooSeok-Min KangHsiang-Chi WangSue LeeYoungkeun Ahn
Published in: International journal of heart failure (2022)
In real-world practice, 95% patients started with low and moderate doses of sacubitril/valsartan. Many patients experienced dose up-titration during follow-up; 30% reached the target dose. Cardiac reverse remodelling was reflected by a profound NT-proBNP level and LV size reduction, and LVEF increment. This study confirms the gap in treatment patterns between clinical trials and real-world practice.
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