A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 7.

Manabu KubotaChie SekiYasuyuki KimuraKeisuke TakahataHitoshi ShimadaYuhei TakadoKiwamu MatsuokaKenji TagaiYasunori SanoYasuharu YamamotoMaki OkadaTatsuya KikuchiMasanori IchiseKazunori KawamuraMing-Rong ZhangMakoto Higuchi

Published in: European journal of nuclear medicine and molecular imaging (2021)

We have provided the first demonstration of PET visualization of PDE7 in human brains. 11C-MTP38 is a promising novel PET ligand for the quantitative investigation of central PDE7.

Keyphrases

endothelial cells
pet ct
positron emission tomography
computed tomography
induced pluripotent stem cells
pet imaging
pluripotent stem cells
high resolution