Cognitive profiles and associated structural brain networks in a multimorbid sample of marginalized adults.
Kristina M GicasAndrea A JonesWilliam J PanenkaChantelle GiesbrechtDonna J LangFidel Vila-RodriguezOlga LeonovaAlasdair M BarrRic M ProcyshynWayne SuAlexander RauscherA Talia VertinskyTari BuchananG William MacEwanAllen E ThorntonWilliam G HonerPublished in: PloS one (2019)
The cortical thickness network differences of Cluster 3 suggest that major disruptions in structural connectivity underlie cognitive dysfunction in a subgroup of people who have a high multimorbid illness burden and who are vulnerably housed or homeless. The origins, and possible plasticity of these structure-function relationships identified with network analysis warrant further study.