Alternate routes to mnm 5 s 2 U synthesis in Gram-positive bacteria.
Marshall JarochGuangxin SunHo-Ching Tiffany TsuiColbie ReedJinjing SunMarko JörgMalcolm E WinklerKelly C RiceTroy A StichPeter C DedonPatricia C Dos SantosValérie de Crécy-LagardPublished in: bioRxiv : the preprint server for biology (2023)
U in several Gram-positive bacteria, including human pathogens. This is another novel example of a non-orthologous displacement in the field of tRNA modification synthesis, showing how different solutions evolve to retain U34 tRNA modifications.