Nestin expression in breast cancer: association with prognosis and subtype on 3641 cases with long-term follow-up.

Karama AslehJennifer R WonDongxia GaoK David VoducTorsten O Nielsen

Published in: Breast cancer research and treatment (2017)

Nestin IHC positivity is associated with the poor clinical outcomes and reduced survival rates that characterize the gene expression basal-like subtype. This easily applicable tool identifies ER+ poor prognosis basal phenotype patients that are currently being missed by "Triple negative" or "Core basal" IHC definitions.

Keyphrases

poor prognosis
long non coding rna
gene expression
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
genome wide
patient reported outcomes
breast cancer cells
endoplasmic reticulum
breast cancer risk
childhood cancer