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Utilizing type I interferon expression in the identification of antiphospholipid syndrome subsets.

Irene CecchiMassimo RadinJavier Rodríguez-CarrioAjay TambralliJason S KnightSavinio Sciascia
Published in: Expert review of clinical immunology (2021)
To date, the scarce available data as well as methodological and technical heterogeneity among studies limit the comparability of the results, thus requiring further validation to translate these findings to routine clinical practice. Therefore, further research is required in pursuit of more nuanced patient profiling and the development of new immunomodulatory therapeutic strategies for APS beyond anti-coagulant and antiplatelet agents.
Keyphrases
  • clinical practice
  • single cell
  • poor prognosis
  • case report
  • electronic health record
  • dendritic cells
  • peripheral blood
  • big data
  • case control
  • bioinformatics analysis
  • machine learning