Effects of Colchicine on Cardiovascular Outcomes in Patients with Coronary Artery Disease: A Systematic Review and One-Stage and Two-Stage Meta-Analysis of Randomized-Controlled Trials.

Yao Neng TeoYao Hao TeoNicholas L SynMing Wei GohCeline Shuen Yin YoongChi-Hang LeeMark Yan-Yee ChanPing ChaiTiong-Cheng YeoChing-Hui Sia

Published in: High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension (2021)

Given the significant benefits of colchicine demonstrated on IPD, and its consistent benefits when analyzed using aggregate data meta-analysis, we propose that colchicine may be considered as an additional pharmacological adjunct to the first line therapy for patients with coronary artery disease.

Keyphrases

systematic review
electronic health record
big data
randomized controlled trial
case control
artificial intelligence