Percutaneous CT-Guided Microwave Ablation Combined with Pedicle Screw Fixation Followed by Vertebroplasty (MASFVA): Initial Experience of a Minimally Invasive Treatment of Vertebral Metastases with Extension to the Vertebral Pedicle.
Claudio PuscedduSalvatore MarsicoDaniele DerudasNicola BallicuLuca MelisCarlo de FeliceAlessandro CalabreseDomiziana SantucciEliodoro FaiellaPublished in: Current oncology (Toronto, Ont.) (2023)
(1) Background: The aim of this study was to retrospectively evaluate the safety and efficacy of a combined CT-guided percutaneous microwave ablation (MWA) and pedicle screw fixation followed by vertebroplasty (MASFVA) for the treatment and stabilization of painful vertebral metastases with vertebral pedicle involvement. (2) Methods: from January 2013 to January 2017 11 patients with 16 vertebral metastatic lesions (7 men and 5 women; mean age, 65 ± 11 years) with vertebral metastases underwent CT-guided microwave ablation and screw fixation followed by vertebroplasty (MASFVA). Technical success, complication rate, pain evaluation using a visual analogue scale (VAS), Oswestry Disability Index (ODI) and local tumor control were examined. (3) Results: Technical success rate was 100%. No procedure-related major complications occurred. VAS score decreased from 6.8 ± 0.7 to 0.6 ± 0.6. ODI score decreased from 3.1 ± 0.7 to 1.2 ± 0.4. All patients could walk independently without neurological complication after one week from the procedure. No new bone fractures or local disease recurrence occurred during a median follow-up of 12 months. (4) Conclusions: Our results suggest that MWA and percutaneous pedicle screw fixation followed by vertebroplasty for the treatment of painful vertebral metastases is a safe and effective procedure for painful vertebral metastases with vertebral pedicle involvement, allowing pain relief and local tumor control.
Keyphrases
- minimally invasive
- bone mineral density
- robot assisted
- radiofrequency ablation
- postmenopausal women
- computed tomography
- chronic pain
- body composition
- end stage renal disease
- multiple sclerosis
- ejection fraction
- squamous cell carcinoma
- image quality
- clinical trial
- randomized controlled trial
- newly diagnosed
- neuropathic pain
- combination therapy
- peritoneal dialysis
- dual energy
- blood brain barrier
- study protocol
- ultrasound guided
- patient reported outcomes
- double blind