Ultraviolet B Downregulated Aquaporin 1 Expression via the MEK/ERK pathway in the Dermal Fibroblasts.

Won Oh Kim Sung-Ae Kim Yun-A Jung Seong-Il Suh Young Wook Ryoo

Published in: Annals of dermatology (2020)

We concluded that AQP1 expression was down-regulated by repeated exposure of UVB via MEK/ERK activation pathways. The AQP1 reduction by UVB lead to changes of physiological functions in dermal fibroblasts, which might be associated with the occurrence and development of UVB induced photoaging.

Keyphrases

pi k akt
poor prognosis
signaling pathway
cell proliferation
risk assessment
extracellular matrix
binding protein
long non coding rna
diabetic rats
wound healing